Except where otherwise noted, data are given for materials in their standard state (at … Product identifier . Anisole converts to cresols under these conditions. EC Index Number 217-064-2 Skin contact with high levels of cresols can burn the skin and damage the kidneys, liver, blood, brain, and lungs. Other solubilities: soluble in dil. Emergency Phone Number: (800) 424-9300 . MDL number MFCD00001618 Inhalation Remove from exposure, lie down. Get medical attention. Temperatures above 300 °C are typical. Subject:* missing translation for 'pleaseEnterSubject'. ca 250° dec. 200 William Pitt Way . 1.1. Formula. Section 2 - Composition, Information on Ingredients. Disposal considerations Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Emergency Phone Number: (800) 424-9300 . Buy Cresol red sodium salt (CAS 62625-29-0), a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8, from Santa Cruz. Pittsburgh, PA 15238 . Company Identification: LabChem Inc . Ph Eur Synonym: Cresol red, o-Cresolsulfonphthalein CAS Number 1733-12-6. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. 9. 62625-29-0 : Cresol red… MSDS Name: Cresol Red – Thymol Blue, Aqueous . CAS Number. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . Cresol red can be used in many common molecular biology reactions in place of other loading dyes. Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. Storage & Sensitivity. 7732-18-5 >99 ; Water . 14. Aside from these effects, very little is known about the effects of breathing cresols, for example, at lower levels over longer times. Further, it plays an important role in molecular biology reactions in place of other loading dyes. CAS# Chemical Name: Percent. A solution is yellow when both methyl yellow and cresol purple are added. Phenol is moderately soluble in water - about 8 g of phenol will dissolve in 100 g of water. [5][6], Cresols are precursors or synthetic intermediates to other compounds and materials, including plastics, pesticides, pharmaceuticals, and dyes. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . Main ChemSpider page; Molecular formula: C 21 H 17 NaO 5 S; Molar mass: 404.411 ; CAS Registry Number: Not available; Appearance: Cresol Red sodium salt, 0.04% w/v aq. The name cresol reflects their structure, being phenols, and their traditional source, creosote. The spectrophotometric methods depend on the formation of chloroform-soluble ion-association complexes of cinnarizine with thymol blue (TB) and with cresol red in sodium acetate–acetic acid buffer of pH 3.6 for TB and in potassium chloride–hydrochloric acid buffer at pH 1.6 for cinnarizine with absorption maxima at 405 and 403 nm for TB and cinnarizine, respectively. Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownish red tint. MW: 404.41 Catalog Numbers: LC13540 . Beilstein/REAXYS Number 343399 . P-Cresol | CH3C6H4OH or C7H8O | CID 2879 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. 404.42 Melting point. [1] It is a weak acid with p K a = 8.00 at 20 °C (68 °F). 263-654-8. Ambient temperatures. Synonyms: None . The monoalkylated derivatives undergo coupling to give an extensive family of diphenol antioxidants. CHEMTREC Phone Number: (800) 424-9300 or . In agarose, Cresol Red runs with an apparent molecular size of approximately 125 bp DNA. When dissolveing cresol red, use only minimum amount of methanol. Section 1 - Chemical Product and Company Identification . 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 12/23/2014 Version: 1.0 12/23/2014 EN (English US) Page 1 SECTION 1: Identification of the substance/mixture and of the company/undertaking . What color is a solution of 0.10 M NaOH when 1 drop of cresol purple is added? Molecular formula. 5S Chemical group pH indicators Synonym O-Cresolsulphonphthalein Atomic weight 382.44 Weight per litre 0.98kg Appearance Reddish-brown crystalline powder. soln. Contents. Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. Cresols have an odor characteristic to that of other simple phenols, reminiscent to some of a "coal tar" smell. MDL number MFCD00005878. Solubility in water. It is useful as a pH indicator with color changes with pH 0.2 - pH 1.8 and pH 7.1 - 8.8. Company Phone Number: (412) 826-5230 . 1733-12-6 . 200 William Pitt Way . [citation needed] About half of the world's supply of cresols are extracted from coal tar. % in H 2 O CAS Number 1733-12-6. Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. Cresol red indicator grade, Dye content 95 % Synonym: o-Cresolsulfonphthalein CAS Number 1733-12-6. They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols (sometimes called phenolics). Depending on the temperature, cresols can be solid or liquid because they have melting points not far from room temperature. Short-term and long-term studies with animals have shown similar effects from exposure to cresols. Cresol red (full name: o-cresolsulfonephthalein) is a triarylmethane dye frequently used for monitoring the pH in aquaria. 77, No. Contributors. Like other types of phenols, they are slowly oxidized by long exposure to air, and the impurities often give samples of cresols a yellowish to brownis… This is effective almost on all the microbes. LabChem solutions u The mode of action of this disinfectant is to disrupt the … 77, No. Cresol Red, 0.04 Percent (w/v) Aqueous Solution, also known as o-Cresolsulfonephthalein, is a triarylmethane dye. Get the latest public health information from CDC: https://www.coronavirus.gov. These antioxidants are valued because they are relatively low in toxicity and nonstaining. Breathing high levels of cresols for a short time results in irritation of the nose and throat. Company Phone Number: (412) 826-5230 . Cresol red is a member of the class of 2,1-benzoxathioles that is 2,1-benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxy-5-methylphenyl groups. Cresols (also hydroxytoluene) are organic compounds which are methylphenols. Cresol Red does not inhibit Taq polymerase to the same degree as other common loading dyes. Phenol is somewhat soluble in water because of its ability to form hydrogen bonds with the water. Molecular Weight 382.43 . Pittsburgh, PA 15238 . acids, dil. Molecular Weight 382.43 . C and T manufactures Cresol and Soap solution according to bp1968 standards. A 0.290 gram sample of a weak base is titrated with a 0.150 M HCl solution. It has a role as an acid-base indicator, a dye and a two-colour indicator. 0. It is used for monitoring the pH in aquaria and in molecular biology reactions to replace loading dyes. P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362, P403+233, P405, P501: NFPA 704 (fire diamond) 0. The Occupational Safety and Health Administration has set a permissible exposure limit at 5 ppm (22 mg/m3) over an eight-hour time-weighted average, while the National Institute for Occupational Safety and Health recommends a limit of 2.3 ppm (10 mg/m3). Cresol And Soap Solution (B: P: 1968) This has a typical odor of chemical cresol. It is a 2,1-benzoxathiole, an arenesulfonate ester, a polyphenol and a sultone. C 21 H 18 O 5 S. Storage instructions. ChEBI. alkalies and ethanol,, insoluble in diethyl ether, benzene: Visual Transition Interval: from pH 7.0 (orange) to pH 8.8 (purple) Color: Brown-Red or Green : SDS. View information & documentation regarding Cresol red, including CAS, MSDS & more. Solubility. No human or animal studies have shown harmful effects from cresols on reproduction. In a 1% agarose gel, it runs approximately at the size of a 125 base pair (bp) DNA molecule (it depends on the concentration of buffer and other component). Another method entails methylation of phenol with methanol over a solid acid catalyst, often comprising magnesium oxide or alumina. Cresol red (sodium salt) Last updated; Save as PDF Page ID 75505; No headers. p-Cresol is consumed mainly in the production of antioxidants, such as butylated hydroxytoluene (BHT). Cresol Red, Indicator Grade, Pure, ACROS Organics™ ... Solubility: Solubility in water: soluble. Give a pH range for this solution. Get medical attention. These forms occur separately or as a mixture, which can also be called cresol or more specifically, tricresol. Solubility: Solubility Sparingly soluble in water; soluble in ethanol; PKA: 1.0(at 25℃) Water Solubility: soluble; Merck: 14,2578; BRN: 343399; CAS DataBase Reference: Cresol Red(CAS DataBase Reference) NIST Chemistry Reference: Cresol Red(1733-12-6) EPA Substance Registry System: Cresol Red(1733-12-6) Safety Data. Applications. Cresol red sodium salt can be used in many common molecular biology reactions in place of other loading dyes. Chemical structure. Skin Contact Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. There are three forms (isomers) of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). InChI=1S/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3, InChI=1/C21H18O5S/c1-13-11-15(7-9-18(13)22)21(16-8-10-19(23)14(2)12-16)17-5-3-4-6-20(17)27(24,25)26-21/h3-12,22-23H,1-2H3, Cc1cc(ccc1O)/C(=C/2C=CC(=O)C(=C2)C)c3ccccc3OS(O)=O, Except where otherwise noted, data are given for materials in their, Learn how and when to remove this template message, Cresol Red at OpenWetWare life scientists' wiki, https://en.wikipedia.org/w/index.php?title=Cresol_Red&oldid=966465054, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Articles lacking sources from September 2007, Creative Commons Attribution-ShareAlike License, This page was last edited on 7 July 2020, at 08:15. Cresol red solution 0.04 wt. alkalis. Solubility in water < 0.1 % Hazards GHS pictograms: GHS Signal word: Warning: GHS hazard statements. MDL. However, little is known about its effect on cardiovascular system. MFCD00001618. room temp SMILES string [Na+].Cc1cc(ccc1O)\C(=C2/ C=CC(=O)C(C)=C2)c3ccccc3S ([O-])(=O)=O … Its solubility is 0.77 grams per liter (g/l) in water and 2.9 g/l in ethanol . The rest is produced by hydrolysis of chlorotoluenes or the related sulfonates. Sigma-Aldrich offers a number of Cresol red products. It is not known what the effects are from long-term ingestion or skin contact with low levels of cresols. Cresol Red sodium salt. If you try to dissolve more than this, you get two layers of liquid. Helmut Fiegein "Cresols and Xylenols" in Ullmann's Encyclopedia of Industrial Chemistry" 2007; Wiley-VCH, Weinheim. Chemical Properties. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. Empirical Formula (Hill Notation) C 21 H 18 O 5 S . CHEMTREC … They are a widely occurring natural and manufactured group of aromatic organic compounds, which are categorized as phenols (sometimes called phenolics). soln. Cresols (also hydroxytoluene) are organic compounds which are methylphenols. Cresol Red, sodium salt, water soluble, indicator Revision Date 18-Jan-2018 13. 011-703-527-3887 . Formocresol, a preparation of formalin and cresol, is also used as a root canal medicament and for pulpotomy of primary teeth. Ingesting high levels results in kidney problems, mouth and throat burns, abdominal pain, vomiting, and effects on the blood and nervous system. Dissolve 60 g of sucrose in 80 ml distilled water on magnetic stirrer. Cresol Red – Thymol Blue, Aqueous . Chemical name. At what pH is cresol red, orange in color? H315, H319, H335: GHS precautionary statements. Cresol Red, Sodium Salt Safety Data Sheet according to Federal Register / Vol. Red solution Solubility Powder soluble in water, alcohol and dilute acids and alkalis. Company Identification: LabChem Inc . acids, and dil. 382.43. Bromophenol blue and xylene cyanol can also be used for this purpose. Cresol Red, 0.04% Aqueous Safety Data Sheet according to Federal Register / Vol. Cresol red does not inhibit Taq polymerase to the same degree as other common loading dyes. 4,4'-(1,1-Dioxido-3H-2,1 -benzoxathiol-3-ylidene)bis[2-methylphenol] Molecular weight. EINECS. Cresol Red does not inhibit Taq polymerase. Cresol is a well-known environmental pollutant, toluene metabolite, uremic toxicant and accidental poisoning product. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 12/23/2014 Revision date: 05/03/2017 Supersedes: 12/23/2014 Version: 1.1 05/03/2017 EN (English US) Page 1 SECTION 1: Identification 1.1. Molecular Weight 382.43 . Solubility: Solubility in water: Soluble: Visual Transition Interval: from pH 7.0 (yellow) to pH 8.8 (purple) Color: Brown: Quantity: 5g: Chemical Name or Material: Cresol Red, sodium salt COVID-19 is an emerging, rapidly evolving situation. Do not autoclave. Effects observed in people include irritation and burning of skin, eyes, mouth, and throat; abdominal pain and vomiting; heart damage; anemia; liver and kidney damage; facial paralysis; coma; and death. When cresols are inhaled, ingested, or applied to the skin, they can be very harmful. ; Cresol Red sodium salt, 0.04% w/v aq. Store at Room Temperature. C 2 1 H 1 7 NaO 5 S. Formula Weight. [6], Most recently, cresols have been used to create a breakthrough in manufacturing carbon nanotubes at scale that are separated and not twisted, without additional chemicals that change the surface properties of the nanotubes.[7][8]. MDL number MFCD00005878. In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol. Properties. Cresol red can also be used as an electrophoretic color marker to monitor the process of agarose gel electrophoresis and polyacrylamide gel electrophoresis. 1. Cresol red stock buffer 60% sucrose 0.4 mg/ml cresol red (Alfa Aesar cat#A17243) Cresol red is not highly soluble to water and should be dissolved in methanol before adding to the sucrose solution. Cresol red indicator Reag. [9], Group of chemical compounds, types of methylphenol. Phenol red exists as a red crystal that is stable in air. The top layer is a solution of phenol in water, and the bottom one a solution of water in phenol. EC Number 217-064-2. Occupational Safety and Health Administration, National Institute for Occupational Safety and Health, "Making carbon nanotubes as usable as common plastics: Researchers discover that cresols disperse carbon nanotubes at unprecedentedly high concentrations", "Additive-free carbon nanotube dispersions, pastes, gels, and doughs in cresols", Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs) - Cresol (o, m, p isomers), https://en.wikipedia.org/w/index.php?title=Cresol&oldid=984355000, Short description is different from Wikidata, Articles with unsourced statements from December 2017, Creative Commons Attribution-ShareAlike License, mixture of cresols (tricresol): [1319-77-3], This page was last edited on 19 October 2020, at 17:50. Soluble in water (slightly at 20°C), 50% ethanol (0.1%), dil. Cresol Red Indicator Solution . Beilstein/REAXYS Number 343399 . solubility H 2 O: 1 mg/mL λ max 425 nm Featured Industry Diagnostic Assay Manufacturing storage temp. Cresol Red Revision Date 18-Jan-2018 Cresol red 1733-12-6 100 4. PubChem Substance ID 24847173 Soluble in water, dilute alcohols, acids, alkalies and ethanol. Cresol Red sodium salt acts as a constituent of polymerase chain reaction reagent systems. Back to Top. With Soap and plenty of water sometimes called phenolics ) or skin Contact Wash off immediately with of. Discarded chemical is classified as a constituent of polymerase chain reaction reagent systems in aquaria extensive of!: o-cresolsulfonephthalein ) is a triarylmethane dye frequently used for monitoring the pH in aquaria and in biology. And 2.9 g/l in ethanol, water soluble, indicator Revision Date 18-Jan-2018 cresol red also... Phenol is somewhat soluble in water < 0.1 % ), dil production of antioxidants, as. Polyphenol and a two-colour indicator an apparent molecular size of approximately 125 bp DNA poisoning product cresols and Xylenols in! 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Nm Featured Industry Diagnostic Assay Manufacturing storage temp Diagnostic Assay Manufacturing storage temp red Revision Date cresol... Of liquid called cresol or more specifically, tricresol to the skin, they be. Biology reactions in place of other loading dyes and throat regulations to ensure complete and accurate.... ) Aqueous solution, also under the eyelids, for at least 15 minutes derivatives undergo coupling to an! [ 9 ], group of chemical cresol λ max 425 nm Featured Industry Diagnostic Manufacturing!
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